60% of worldwide deaths are expected to be caused by lifestyle-related diseases. According to literature, psychological characteristics are in the base of efficacy for conducting a healthy lifestyle (HL). Aim: This study attempted to decipher factors related to low-efficacy for physical activity (PA) among the Israeli adult population (18+), in extreme case study COVID-19 pandemic; including a rise in homestay and work-from-home. Method: Fieldwork was based on an applied participatory design approach including 13 in-depth semi-structured interviews with 8 experts and 5 informants and an online quotative/qualitative questionnaire with 35 informants. Main findings: Aiding factors and blockers were identified as existing on three behavior ranges: (a) Locus of control range which includes a blocker of ‘lack of available supportive self-tailored connection and a blocker of putting responsibility for being physically active on factors external to the self, (b) range of Coherence which includes a blocker of ‘healthy lifestyle as a stress-causing burden’ and a blocker of ‘difficulty in organizing daily activities’, and (c) range of prioritizing activities based on short vs. long term vision which included the blocker ‘attraction to comfort of the present’ and 'procrastination'. Conclusions: The need for re-organizing workers' health plans, that followed COVID-19, is responded by characterizing an AI-based app that encourages virtual PA meetings within PA low-efficacy individuals. The app is based on behavior-drive-for-action triggers which include: personal characterization recognition, non-judgmental community relationships accompanied with personal supportive connection, response for specific current needs, incentive and feedback based environment, and measurable behavior change. The app's environment encourages change in self-perception of self-efficacy and the ability to maintain sufficient PA.